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Article

Interaction between LRP5 and periostin gene polymorphisms on serum periostin levels and cortical bone microstructure.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Feb 2018

Pepe J, Bonnet N, Herrmann F R, Biver E, Rizzoli R, Chevalley T, Ferrari S L

Abstract excerpt

We investigated the interaction between periostin SNPs and the SNPs of the genes assumed to modulate serum periostin levels and bone microstructure in a cohort of postmenopausal women. We identified an interaction between LRP5 SNP rs648438 and periostin SNP rs9547970 on serum periostin levels and on radial cortical porosity. PURPOSE: The purpose of this study is to investigate the interaction between periostin...

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Source

Identifiers

PMID: 29038835
DOI: 10.1007/s00198-017-4272-0

Genes

LRP5
ESR1
SOST
SPTBN1
TNFSF11
BMP2
CTNNB1
ESR2
LRP6
PTH
WNT16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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