Article
Generation and characterization of a human induced pluripotent stem (iPS) cell line derived from an acute myeloid leukemia patient evolving from primary myelofibrosis carrying the CALR 52bp deletion and the ASXL1 p.R693X mutation.
Stem cell research - 1 Oct 2017
Gomez Limia Cintia E, Devalle Sylvie, Reis Marcelo, Sochacki Jaroslaw, Carneiro Mayra, Madeiro da Costa Rodrigo, D'Andrea Mariana, Padilha Telma, Zalcberg Ilana R, Solza Cristiana, Daumas Adelmo, Rehen Stevens, Monte-Mór Bárbara, Bonamino Martín H
Abstract excerpt
Peripheral blood sample was donated by a 61years old female patient diagnosed with acute myeloid leukemia secondary to a primary myelofibrosis harboring the 52-bp deletion in the CALR gene (c.1092_1143del, p.L367fs*46) and the R693X mutation in the ASXL1 gene (c.2077C>T, p.R693X). CD34+ cells were isolated from the sample and subjected to the reprogramming procedure by using the Sendai virus carrying the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.