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Article

Generation of an induced pluripotent stem cell line (ZJUi007-A) from a 11-year-old patient of Fabry disease.

Stem cell research - 1 Aug 2021

Zhu Yuqing, Zhang Li, Wang Gang, Zhao Jing, Hou Xiaolin, Wu Hangdi, Xu Yuming, Mao Jianhua, Liu Zhihong, Zhang Jin

Abstract excerpt

PBMCs were collected from a patient with a novel GLA gene mutation (c.140G > A) which contributed to Fabry disease. Subsequently, an induced pluripotent stem cell (iPSC) line was derived using an episomal reprogramming method that transfer the reprogramming plasmids expressing OCT3/4, SOX2, KLF4, LIN28 and L-MYC into the PBMCs. The expected mutation in the iPSC line was confirmed by Sanger sequencing, while the...

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Source

Identifiers

PMID: 34365103
DOI: 10.1016/j.scr.2021.102475

Genes

GLA
KLF4
MYC
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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