Article
A new rare allele at the CGG repeat polymorphism in the first intron of human c-H-ras gene.
In vivo (Athens, Greece) - 1 Jan 2000
Kotsinas A, Gorgoulis V G, Zacharatos P, Liloglou T, Leonardou P, Bramis J, Troupis T G, Fotiadis C, Field J K, Kittas C
Abstract excerpt
We have examined a region in the first intron of the human c-H-ras gene containing a CGG repeat. This region was previously shown to be variable in length. The length variation was attributed to the presence of the CGG repeat after estimation of its electrophoretic mobility. In the present report we have characterized in detail this region by PCR-RFLP and automated sequencing, in a total of 102 histologically...
Topics
- Alleles
- Base Sequence
- Breast Neoplasms
- Female
- Genes, ras
- Humans
- Introns
- Lung Neoplasms
- Molecular Sequence Data
- Polymorphism, Genetic
- Trinucleotide Repeats
