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Article

Digging deep into Golgi phenotypic diversity with unsupervised machine learning.

Molecular biology of the cell - 1 Dec 2017

Hussain Shaista, Le Guezennec Xavier, Yi Wang, Dong Huang, Chia Joanne, Yiping Ke, Khoon Lee Kee, Bard Frédéric

Abstract excerpt

The synthesis of glycans and the sorting of proteins are critical functions of the Golgi apparatus and depend on its highly complex and compartmentalized architecture. High-content image analysis coupled to RNA interference screening offers opportunities to explore this organelle organization and the gene network underlying it. To date, image-based Golgi screens have based on a single parameter or supervised...

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Identifiers

PMID: 29021342
DOI: 10.1091/mbc.E17-06-0379
PMCID: PMC5706995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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