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Article

High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulation.

The Journal of cell biology - 5 Jan 2026

Cao Xun, Peng Yiming, Yang Mengyuan, Gan Mengling, Zhang Di, Zhou Shiyue, Takao Daisuke

Abstract excerpt

Recent advances in quantitative bioimage analysis have enabled detailed analyses of cellular and subcellular morphological features, enhancing our understanding of cellular functions. Here, we introduce an image-based phenotyping pipeline designed for the comprehensive analysis of dynamic organelle morphology, particularly the Golgi apparatus and cilia, during cell cycle progression. Our approach emphasizes...

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PMID: 41236476
DOI: 10.1083/jcb.202503083
PMCID: PMC12617404

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AURKA

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