Article

The expression of PKM1 and PKM2 in developing, benign, and cancerous prostatic tissues

2023-09-29

Abstract excerpt

Neuroendocrine prostate cancer (NEPCa) is the most aggressive type of prostate cancer. However, energy metabolism, one of the hallmarks of cancer, in NEPCa has not been well studied. Pyruvate kinase M (PKM), which catalyzes the final step of glycolysis, has two main splicing isoforms, PKM1 and PKM2. PKM2 is known to be upregulated in various cancers, including prostate adenocarcinoma (AdPCa). In this study, we use...

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Literature Corpus work: 4bcaceb6-743b-5ef2-9d43-19f7fb973b17
DOI: 10.1101/2023.09.27.559832

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