Article
Mutants of the Flavoprotein iLOV as Prospective Red-Shifted Fluorescent Markers.
The journal of physical chemistry. B - 2 Nov 2017
Khrenova Maria G, Meteleshko Yulia I, Nemukhin Alexander V
Abstract excerpt
We report on novel variants of the flavin-based fluorescent protein iLOV with absorption and emission optical bands shifted to the longer wavelengths relative to their precursor. First attempts (J. Phys. Chem. B 2015, 119, 5176; 2016, 120, 3344) to improve spectral properties of iLOV, a fluorescent marker in living cells, showed that single point mutation Q489K could lead to a promising variant, but its...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
