Article
Failure to Recover from Proactive Semantic Interference and Abnormal Limbic Connectivity in Asymptomatic, Middle-Aged Offspring of Patients with Late-Onset Alzheimer's Disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2017
Sánchez Stella M, Abulafia Carolina, Duarte-Abritta Barbara, de Guevara M Soledad Ladrón, Castro Mariana N, Drucaroff Lucas, Sevlever Gustavo, Nemeroff Charles B, Vigo Daniel E, Loewenstein David A, Villarreal Mirta F, Guinjoan Salvador M
Abstract excerpt
BACKGROUND: We have obtained previous evidence of limbic dysfunction in middle-aged, asymptomatic offspring of late-onset Alzheimer's disease (LOAD) patients, and failure to recover from proactive semantic interference has been shown to be a sensitive cognitive test in other groups at risk for LOAD. OBJECTIVE: To assess the effects of specific proactive semantic interference deficits as they relate to functional...
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