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Article

Proper joint analysis of summary association statistics requires the adjustment of heterogeneity in SNP coverage pattern.

Briefings in bioinformatics - 27 Nov 2018

Zhang Han, Wheeler William, Song Lei, Yu Kai

Abstract excerpt

As meta-analysis results published by consortia of genome-wide association studies (GWASs) become increasingly available, many association summary statistics-based multi-locus tests have been developed to jointly evaluate multiple single-nucleotide polymorphisms (SNPs) to reveal novel genetic architectures of various complex traits. The validity of these approaches relies on the accurate estimate of z-score...

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PMID: 28981575
DOI: 10.1093/bib/bbx072
PMCID: PMC6454427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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