Article
MMP-8 C-799 T, Lys460Thr, and Lys87Glu variants are not related to risk of cancer.
BMC medical genetics - 21 Oct 2019
Zhang Li-Feng, Zhu Li-Jie, Zhang Wei, Yuan Wei, Song Ning-Hong, Zuo Li, Mi Yuan-Yuan, Wang Zeng-Jun, Zhang Wei
Abstract excerpt
BACKGROUND: Several studies have focused on the relationship between MMP-8 variants and cancer risk, but they have been unsuccessful in drawing reliable conclusions. METHODS: We employed odds ratio (OR) together with 95% confidence interval (CI) to assess the correlation between MMP-8 C-799 T, Lys460Thr, and Lys87Glu polymorphisms and cancer risk. We further employed in silico tools to evaluate the effect of...
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