Article
Genetic polymorphisms in matrix metalloproteinases (MMPs) and tissue inhibitors of MPs (TIMPs), and bladder cancer susceptibility.
BJU international - 1 Dec 2013
Wieczorek Edyta, Reszka Edyta, Jablonowski Zbigniew, Jablonska Ewa, Krol Magdalena Beata, Grzegorczyk Adam, Gromadzinska Jolanta, Sosnowski Marek, Wasowicz Wojciech
Abstract excerpt
OBJECTIVES: To elucidate genetic polymorphisms of the matrix metalloproteinases (MMPs) MMP1 (rs1799750), MMP2 (rs243865), MMP9 (rs3918242), MMP12 (rs2276109) and tissue inhibitors of MMPs (TIMPs) TIMP1 (rs2070584) and TIMP3 () genes that may be involved in susceptibility to bladder cancer (BC). PATIENTS AND METHODS: We enrolled 241 patients with BC and 199 controls. Genomic DNA samples were extracted...
