Article
Functional polymorphisms in the matrix metalloproteinase genes and their association with bladder cancer risk and recurrence: a mini-review.
International journal of urology : official journal of the Japanese Urological Association - 1 Aug 2014
Wieczorek Edyta, Wasowicz Wojciech, Gromadzinska Jolanta, Reszka Edyta
Abstract excerpt
Molecular pathogenesis of muscle invasive bladder cancer and non-muscle invasive bladder cancer is incompletely elucidated. It is believed that matrix metalloproteinases, which are involved in the processes of uncontrolled extracellular matrix substrates degradation and participate in modulating the activity of a variety of non-matrix proteins, can contribute to carcinogenesis. Polymorphisms in the MMP genes...
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