Discovery of rare variants for complex phenotypes.

Abstract excerpt

With the rise of sequencing technologies, it is now feasible to assess the role rare variants play in the genetic contribution to complex trait variation. While some of the earlier targeted sequencing studies successfully identified rare variants of large effect, unbiased gene discovery using exome sequencing has experienced limited success for complex traits. Nevertheless, rare variant association studies have...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Exome
• Share to Genetic Predisposition to Disease
• Share to Genetic Variation