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Article

Role of adaptor protein p66Shc in renal pathologies

4 Oct 2017

Abstract excerpt

p66Shc is one of the three adaptor proteins encoded by the Shc1 gene, which are expressed in many organs, including the kidney. Recent studies shed new light on several key questions concerning the signaling mechanisms mediated by p66Shc. The central goal of this review article is to summarize recent findings on p66Shc and the role it plays in kidney physiology and pathology. This article provides a review of the...

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Identifiers

PMID: 28978535
DOI: 10.1152/ajprenal.00414.2017

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