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STAP2 promotes the progression of renal fibrosis via HSP27

12 Nov 2024

Abstract excerpt

BACKGROUND: Renal fibrosis is a key process in the progression from acute kidney injury (AKI) to chronic kidney disease (CKD), while the intricate mechanisms of renal fibrosis remain obscure. While the signal-transducing adaptor protein 2 (STAP2) was well-studied for its notable function in inflammation and immune-related disorders, its specific implication in renal fibrosis remains unclear. This study assessed...

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PMID: 39533293
DOI: 10.1186/s12967-024-05776-6

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