Genetic modifiers of Mendelian disease: Huntington's disease and the trinucleotide repeat disorders.

Abstract excerpt

In the decades since the genes and mutations associated with the commoner Mendelian disorders were first discovered, technological advances in genetic analysis have made finding genomic variation a much less onerous task. Recently, the global efforts to collect subjects with Mendelian disorders, to better define the disorders and to empower appropriate clinical trials, along with improved genetic technologies,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genes, Modifier
• Share to Genetic Predisposition to Disease
• Share to Genome-Wide Association Study