Huntington Disease: Genetics, Prevention, and Therapy Approaches.

Abstract excerpt

Huntington's chorea or Huntington disease (HD) is a late-onset autosomal dominant neurodegenerative disorder caused by a trinucleotide repeat expansion. The multidisciplinary study of HD has been the focus of an international collaborating effort of basic and applied research for several decades. HD was the first human genetic disease mapped using linkage analysis of DNA polymorphisms and became a paradigm for...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Counseling
• Share to Genetic Testing
• Share to Huntingtin Protein