Article
Association study between apolipoprotein E gene polymorphism and diabetic nephropathy in a Taiwanese population.
Genetic testing and molecular biomarkers - 1 Oct 2011
Wen Min-Jie, Lin Chin-Jung, Hung Yi-Jen, Pei Dee, Kuo Shi-Wen, Hsieh Chang-Hsun
Abstract excerpt
BACKGROUND: Diabetic nephropathy (DN) is the most common cause of end-stage renal disease in Taiwan. Recent studies have demonstrated that the gene for apolipoprotein E (APOE) is associated with end-stage renal disease in African Americans. In this study, we aimed to test the hypothesis that common single-nucleotide polymorphisms in the APOE gene might contribute to the development of DN in a Taiwanese population...
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