Article
Role of the rs2274907 allelic variant of the ITLN1 gene in patients with diabetic foot.
Polish archives of internal medicine - 31 May 2017
Mrozikiewicz-Rakowska Beata, Sobczyk-Kopcioł Agnieszka, Szymański Konrad, Nehring Piotr, Szatkowski Patryk, Bartkowiak-Wieczorek Joanna, Bogacz Anna, Aniszczuk Anna, Drygas Wojciech, Płoski Rafał, Czupryniak Leszek
Abstract excerpt
INTRODUCTION Diabetic foot (DF) is a serious complication of diabetes mellitus (DM) that occurs due to neuropathy or atherosclerosis of the lower limbs. Omentin (encoded by the ITLN1 gene) has been implicated as a protective factor in vascular complications of diabetes, likely due to its endothelial vasodilator activity and its anti‑inflammatory actions. However, susceptibility to DF with respect to the allelic...
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