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Study of the Association of EDN1 rs5370 Polymorphism to Type 2 Diabetes Complications

1 Aug 2025

Abstract excerpt

Introduction: Type 2 diabetes mellitus (T2DM) is common in the Arab population. Endothelin-1 (ET-1) is an a vasoconstrictor agent produced by the endothelin-1 gene ( EDN1 ). Circulating ET-1 has been shown to be increased in T2DM. The current examined the association between the EDN1 rs5370 polymorphism and T2DM. Methods: The investigation was a case-control study and included 190 T2DM patients and 120 healthy...

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PMID: 40792066
DOI: 10.2147/ijgm.s537136

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