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Article

DNA variation in the SNAP25 gene confers risk to ADHD and is associated with reduced expression in prefrontal cortex.

PloS one - 1 Jan 2013

Hawi Ziarih, Matthews Natasha, Wagner Joseph, Wallace Robyn H, Butler Tim J, Vance Alasdair, Kent Lindsey, Gill Michael, Bellgrove Mark A

Abstract excerpt

BACKGROUND: The Coloboma mouse carries a ∼2 cM deletion encompassing the SNAP25 gene and has a hyperactive phenotype similar to that of ADHD. Such mice are 3 fold more active compared to their control littermates. Genetic association studies support a role for allelic variants of the human SNAP25 gene in predisposing to ADHD. METHODS/PRINCIPAL FINDINGS: We performed association analysis across the SNAP25 gene in...

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Share to Attention Deficit Disorder with Hyperactivity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23593184
DOI: 10.1371/journal.pone.0060274
PMCID: PMC3625226

Genes

SNAP25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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