Article
Synaptosome-Associated Protein 25 (SNAP25) Gene Association Analysis Revealed Risk Variants for ASD, in Iranian Population.
Journal of molecular neuroscience : MN - 1 Mar 2017
Safari Mohammad Reza, Omrani Mir Davood, Noroozi Rezvan, Sayad Arezou, Sarrafzadeh Shaghayegh, Komaki Alireza, Manjili Fateme Asadzadeh, Mazdeh Mehrdokht, Ghaleiha Ali, Taheri Mohammad
Abstract excerpt
Autism spectrum disorder (ASD) is a common, complex neurological condition, affecting approximately 1% of people worldwide. Monogenic neurodevelopmental disorders which showed autistic behavior patterns have suggested synaptic dysfunction, as a key mechanism in the pathophysiology of ASD. Subsequently, genes involved in synaptic signaling have been investigated with a priority for candidate gene studies. A...
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