Article
Association study of SNAP25 and schizophrenia in Irish family and case-control samples.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2010
Fanous A H, Zhao Z, van den Oord E J C G, Maher B S, Thiselton D L, Bergen S E, Wormley B, Bigdeli T, Amdur R L, O'Neill F A, Walsh D, Kendler K S, Riley B P
Abstract excerpt
SNAP25 occurs on chromosome 20p12.2, which has been linked to schizophrenia in some samples, and recently linked to latent classes of psychotic illness in our sample. SNAP25 is crucial to synaptic functioning, may be involved in axonal growth and dendritic sprouting, and its expression may be decreased in schizophrenia. We genotyped 18 haplotype-tagging SNPs in SNAP25 in a sample of 270 Irish high-density...
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