Article
Family-based association study identifies SNAP25 as a susceptibility gene for autism in the Han Chinese population.
Progress in neuro-psychopharmacology & biological psychiatry - 8 Mar 2021
Wang Ziqi, Li Jun, Zhang Tian, Lu Tianlan, Wang Han, Jia Meixiang, Liu Jing, Xiong Jun, Zhang Dai, Wang Lifang
Abstract excerpt
Autism is a neurodevelopmental disorder with high heritability. Synaptosome associated protein 25 (SNAP25) encodes a presynaptic membrane-binding protein. It plays a crucial role in neurotransmission and may be involved in the pathogenesis of autism. However, the association between SNAP25 and autism in the Han Chinese population remains unclear. To investigate whether single nucleotide polymorphisms (SNPs) in...
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