Article
Whole-exome sequencing analysis of NSCLC reveals the pathogenic missense variants from cancer-associated genes.
Computers in biology and medicine - 1 Sept 2022
Kumar S Udhaya, Balasundaram Ambritha, Cathryn R Hephzibah, Varghese Rinku Polachirakkal, R Siva, R Gnanasambandan, Younes Salma, Zayed Hatem, Doss C George Priya
Abstract excerpt
BACKGROUND: Non-small-cell lung cancer (NSCLC) is the most common type of lung cancer. NSCLC accounts for 84% of all lung cancer cases. In recent years, advances in pathway understanding, methods for discovering novel genetic biomarkers, and new drugs designed to inhibit the signaling cascades have enabled clinicians to personalize therapy for NSCLC. OBJECTIVES: The primary aim of this study is to identify the...
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