Article
Association of XRCC3 rs1799794 polymorphism with survival of glioblastoma multiforme patients treated with combined radio-chemotherapy.
Investigational new drugs - 1 Aug 2021
Pasqualetti Francesco, Gonnelli Alessandra, Orlandi Paola, Palladino Eleonora, Giannini Noemi, Gadducci Giovanni, Mattioni Roberto, Montrone Sabrina, Calistri Elisa, Mazzanti Chiara Maria, Franceschi Sara, Ortenzi Valerio, Scatena Cristian, Zavaglia Katia, Fanelli Giuseppe Nicolo, Morganti Riccardo, Santonocito Orazio, Bocci Guido, Naccarato Giuseppe Antonio, Paiar Fabiola
Abstract excerpt
This study reports the results of a monocentric prospective analysis conducted with the aim of evaluating the impact of XRCC1 rs25487, XRCC3 rs861539, XRCC3 rs1799794, RAD51 rs1801320 and GSTP-1 rs1695 single nucleotide polymorphisms (SNP) on patients with high-grade glioma treated with concomitant radio-chemotherapy. From October 2010 to August 2019, a total of 75 patients aged ≥18 years, with histological...
