Article
Melanocortin Receptor-4 Gene Polymorphisms in Glioblastoma Patients Treated with Concomitant Radio-Chemotherapy.
Molecular neurobiology - 1 Feb 2018
Pasqualetti Francesco, Orlandi Paola, Simeon Vittorio, Cantarella Martina, Giuliani Daniela, Di Desidero Teresa, Gonnelli Alessandra, Delishaj Durim, Lombardi Giuseppe, Sechi Andrea, Sanson Marc, Zagonel Vittorina, Paiar Fabiola, Danesi Romano, Guarini Salvatore, Bocci Guido
Abstract excerpt
Melanocortins are peptides with well-recognized antiinflammatory and neuroprotective activity. No data are currently available on melanocortin receptor-4 (MC4R) gene polymorphisms and tumors, including glioblastomas (GBMs), or their relationship with radiotherapy or chemotherapy. The aim of this study was to evaluate the possible predictive/prognostic role of the MC4R SNPs on GBM patients. Fifty-five patients...
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