Article
X-ray structure of Clostridium perfringens sortase B cysteine transpeptidase.
Biochemical and biophysical research communications - 25 Nov 2017
Tamai Eiji, Sekiya Hiroshi, Maki Jun, Nariya Hirofumi, Yoshida Hiromi, Kamitori Shigehiro
Abstract excerpt
The pathogenesis and infectivity of Gram-positive bacteria are mediated by many surface proteins that are covalently attached to peptidoglycans of the cell wall. The covalent attachment of these proteins is catalyzed by sortases (Srts), a family of cysteine transpeptidases, which are classified into six classes, A - F, based on their amino acid sequences and biological roles. Clostridium perfringens, one of the...
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