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Article

A new model of the mechanism underlying lead poisoning: SNPs in miRNA target region influence the δ-aminolevulinic acid dehydratase expression level.

Epigenomics - 1 Nov 2017

Li Chunping, Wang Miaomiao, Wang Yiqing, Zhang Jinlong, Sun Na

Abstract excerpt

AIM: To determine if SNPs located within the 3'-UTR of δ-aminolevulinic acid dehydratase (ALAD) can alter the risk of lead poisoning and the ALAD gene expression. MATERIALS & METHODS: A case-control study was carried out to find the SNPs in miRNA target region. Luciferase reporter gene assay, qRT-PCR and Western blot was used to determine the relationship between miRNA and SNPs. RESULTS: We found a significant...

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Identifiers

PMID: 28960093
DOI: 10.2217/epi-2016-0180

Genes

ALAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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