Article
18F-16α-17β-Fluoroestradiol Binding Specificity in Estrogen Receptor-Positive Breast Cancer.
Radiology - 1 Mar 2018
Salem Kelley, Kumar Manoj, Powers Ginny L, Jeffery Justin J, Yan Yongjun, Mahajan Aparna M, Fowler Amy M
Abstract excerpt
Purpose To determine the binding specificity of 18F-16α-17β-fluoroestradiol (FES) in estrogen receptor (ER) α-positive breast cancer cells and tumor xenografts. Materials and Methods Protocols were approved by the office of biologic safety and institutional animal care and use committee. By using ER-negative MDA-MB-231 breast cancer cells, clonal lines were created that expressed either wild-type (WT; 231 WT ER)...
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