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Article

Genetic alterations of IDH1 and Vegf in brain tumors.

Brain and behavior - 1 Sept 2017

Veganzones Silvia, de la Orden Virginia, Requejo Lucía, Mediero Beatriz, González María Luisa, Del Prado Náyade, Rodríguez García Carmen, Gutiérrez-González Raquel, Pérez-Zamarrón Alvaro, Martínez Armando, Maestro Marisa L, Zimman Horacio Mario, González-Neira Anna, Vaquero Jesús, Rodríguez-Boto Gregorio

Abstract excerpt

BACKGROUND: This study evaluates the presence of R132H mutation in isocitrate dehydrogenase (IDH1) gene and the vascular endothelial growth factor (VEGF) +936 C/T polymorphism in brain tumors. The impact of these genetic alterations on overall survival (OS) and progression free survival (PFS) was evaluated. METHODS: A cohort of 80 patients surgically treated at Hospital Clínico San Carlos, Madrid, between March...

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Identifiers

PMID: 28948065
DOI: 10.1002/brb3.718
PMCID: PMC5607534

Genes

IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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