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Article

IDH1 mutation of gliomas with long-term survival analysis.

Oncology reports - 1 Nov 2012

Myung Jae Kyung, Cho Hwa Jin, Park Chul-Kee, Kim Seung-Ki, Phi Ji Hoon, Park Sung-Hye

Abstract excerpt

A recurrent mutation affecting codon 132 of the isocitrate dehydrogenase 1 (IDH1) gene has been found in ~5% of primary glioblastomas (GBMs), but in >70% of secondary GBMs or oligodendroglial and astrocytic tumors. We investigated IDH1 mutations in a series of 134 brain tumors to determine the prevalence and prognostic impact of IDH1 mutations. We also examined the correlations among histology, p53 and PTEN...

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Share to Brain Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22922798
DOI: 10.3892/or.2012.1994

Genes

IDH1
MGMT
EGFR
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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IDH1 mutation of gliomas with long-term survival analysis.PMID 22922798Read ↗

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