Article
IDH1 mutations in gliomas: first series from a tertiary care centre in India with comprehensive review of literature.
Experimental and molecular pathology - 1 Aug 2011
Jha Prerana, Suri Vaishali, Sharma Vikas, Singh Geetika, Sharma Mehar Chand, Pathak Pankaj, Chosdol Kunzang, Jha Pankaj, Suri Ashish, Mahapatra Ashok Kumar, Kale Shashank Sharad, Sarkar Chitra
Abstract excerpt
OBJECT: Mutations of the gene encoding isocitrate dehydrogenase (IDH) have been shown in a significant proportion of diffuse gliomas. These mutations are specific to gliomas and their utility for diagnosis and prognostication of these tumors is being proclaimed. The present study was conducted with the aim of assessing frequency of IDH1 mutations in gliomas, their correlation with other molecular alterations...
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