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Article

SKOV3 cells containing a truncated ARID1a protein have a restricted genome-wide response to glucocorticoids.

Molecular and cellular endocrinology - 5 Feb 2018

Stubbs F E, Birnie M T, Biddie S C, Lightman S L, Conway-Campbell B L

Abstract excerpt

AT-rich interacting domain subunit 1a (ARID1a) is an essential SWI/SNF component frequently mutated in human cancers. ARID1a mutations have also been associated with glucocorticoid resistance, potentially related to the well-established role of the SWI/SNF complex in glucocorticoid target gene regulation. Glucocorticoids are steroid hormones important for regulating many physiological processes through the...

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PMID: 28942102
DOI: 10.1016/j.mce.2017.09.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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