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Article

The splicing co-factor Barricade/Tat-SF1 is required for cell cycle and lineage progression in Drosophila neural stem cells.

Development (Cambridge, England) - 1 Nov 2017

Abramczuk Monika K, Burkard Thomas R, Rolland Vivien, Steinmann Victoria, Duchek Peter, Jiang Yanrui, Wissel Sebastian, Reichert Heinrich, Knoblich Juergen A

Abstract excerpt

Stem cells need to balance self-renewal and differentiation for correct tissue development and homeostasis. Defects in this balance can lead to developmental defects or tumor formation. In recent years, mRNA splicing has emerged as an important mechanism regulating cell fate decisions. Here we address the role of the evolutionarily conserved splicing co-factor Barricade (Barc)/Tat-SF1/CUS2 in Drosophila neural...

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PMID: 28935704
DOI: 10.1242/dev.152199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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