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Article

Transcriptional trajectories of human kidney injury progression

14 Nov 2018

Abstract excerpt

BACKGROUND: The molecular understanding of the progression from acute to chronic organ injury is limited. Ischemia/reperfusion injury (IRI) triggered during kidney transplantation can contribute to progressive allograft dysfunction. METHODS: Protocol biopsies (n = 163) were obtained from 42 kidney allografts at 4 time points after transplantation. RNA sequencing-mediated (RNA-seq-mediated) transcriptional...

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PMID: 30429361
DOI: 10.1172/jci.insight.123151

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