Article
PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ.
Molecular and cellular endocrinology - 5 Feb 2018
Ferreira Celio, Prestin Katharina, Hussner Janine, Zimmermann Uwe, Meyer Zu Schwabedissen Henriette E
Abstract excerpt
Genome wide association studies revealed single nucleotide polymorphisms (SNP) located within the promoter of PDZ domain containing protein 1 (PDZK1) to be associated with serum uric acid levels. Since modulation of transporters and particularly of membrane proteins involved in uric acid handling by PDZK1 has previously been reported, the aim of this study was to analyze the impact of the polymorphisms rs1967017,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
