Article
A novel role for ciliary function in atopy: ADGRV1 and DNAH5 interactions.
The Journal of allergy and clinical immunology - 1 May 2018
Sugier Pierre-Emmanuel, Brossard Myriam, Sarnowski Chloé, Vaysse Amaury, Morin Andréanne, Pain Lucile, Margaritte-Jeannin Patricia, Dizier Marie-Hélène, Cookson William O C M, Lathrop Mark, Moffatt Miriam F, Laprise Catherine, Demenais Florence, Bouzigon Emmanuelle
Abstract excerpt
BACKGROUND: Atopy, an endotype underlying allergic diseases, has a substantial genetic component. OBJECTIVE: Our goal was to identify novel genes associated with atopy in asthma-ascertained families. METHODS: We implemented a 3-step analysis strategy in 3 data sets: the Epidemiological Study on the Genetics and Environment of Asthma (EGEA) data set (1660 subjects), the Saguenay-Lac-Saint-Jean study data set (1138...
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