Article
Significant association between SCGB1D4 gene polymorphisms and susceptibility to adenoid hypertrophy in a pediatric population.
Turkish journal of medical sciences - 27 Feb 2017
Özdaş Talih, Özdaş Sibel, Babademez Mehmet Ali, Muz Sami Engin, M Atilla Huntürk, Baştimur Sibel, Izbirak Afife, Kurt Kenan, Öz Işı
Abstract excerpt
BACKGROUND/AIM: Adenoid hypertrophy (AH) is chronic enlargement of the adenoid tissue. The pathophysiology of the disease is unclear. We analyzed SCGB1D4 gene polymorphisms in order to determine the effect of the variants or their genetic combinations on AH. MATERIALS AND METHODS: We genotyped the SCGB1D4 (IIS) gene in 167 participants (95 children with AH and 72 controls) by performing DNA sequencing in blood...
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