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Selecting of a cytochrome P450cam SeSaM library with 3-chloroindole and endosulfan - Identification of mutants that dehalogenate 3-chloroindole.

Biochimica et biophysica acta. Proteins and proteomics - 1 Jan 2018

Kammoonah Shaima, Prasad Brinda, Balaraman Priyadarshini, Mundhada Hemanshu, Schwaneberg Ulrich, Plettner Erika

Abstract excerpt

Cytochrome P450cam (a camphor hydroxylase) from the soil bacterium Pseudomonas putida shows potential importance in environmental applications such as the degradation of chlorinated organic pollutants. Seven P450cam mutants generated from Sequence Saturation Mutagenesis (SeSaM) and isolated by selection on minimal media with either 3-chloroindole or the insecticide endosulfan were studied for their ability to...

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PMID: 28923662
DOI: 10.1016/j.bbapap.2017.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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