Article
Computational molecular explanation of Soybean AHAS resistance from P197S mutation.
Plant physiology and biochemistry : PPB - 1 Aug 2023
Ustun Rustem, Chalmers Gordon, Tehrani Daniel, Uzun Bulent
Abstract excerpt
The first enzyme in the pathway involving branched-chain amino is acetohydroxyacid synthase (AHAS, E.C. 2.2.1.6), which is inhibited by five commercial herbicide families. In this work a computational study of a point mutation of Proline-197-Serine of the Soybean AHAS enzyme, which was obtained by mutagenesis, explains the latter's S197 resistance to the commonly used Chlorsulfuron. Using protein-ligand docking...
Topics
- Glycine max
- Sulfonamides
- Herbicides
- Mutation
- Amino Acids
- Acetolactate Synthase
- Herbicide Resistance