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Article

Effects of the Mammalian Target of Rapamycin Inhibitor Everolimus on Hepatitis C Virus Replication In Vitro and In Vivo.

Transplantation proceedings - 1 Oct 2017

Frey A, Ecker E-M, Piras-Straub K, Walker A, Hofmann T G, Timm J, Singer B B, Gerken G, Herzer K

Abstract excerpt

BACKGROUND: The influence of immunosuppressants on hepatitis C virus (HCV) re-infection after liver transplantation, particularly mammalian target of rapamycin inhibitors, remains unclear. The aim of our study was to analyze the influence of everolimus (EVR) on HCV replication activity in the context of underlying molecular mechanisms, with focus on the pro-myelocytic leukemia protein (PML). METHODS: HCV viral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28923653
DOI: 10.1016/j.transproceed.2017.04.012

Genes

PML

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