Treatment of recurrent HCV infection following liver transplantation: results of a multicenter, randomized, versus placebo, trial of ribavirin alone as maintenance therapy after one year of PegIFNα-2a plus ribavirin.

doi:10.1016/j.jhep.2012.04.022

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Article

Treatment of recurrent HCV infection following liver transplantation: results of a multicenter, randomized, versus placebo, trial of ribavirin alone as maintenance therapy after one year of PegIFNα-2a plus ribavirin.

Journal of hepatology - 1 Sept 2012

Calmus Yvon, Duvoux Christophe, Pageaux Georges, Wolf Philippe, Rostaing Lionel, Vanlemmens Claire, Botta-Fridlund Danielle, Dharancy Sébastien, Gugenheim Jean, Durand François, Néau-Cransac Martine, Boillot Olivier, Chazouillères Olivier, Samelson Laurence, Boudjema Karim, Samuel Didier

Abstract excerpt

BACKGROUND & AIMS: We aimed at determining the effect of maintenance therapy with ribavirin alone, after a year of combined peginterferon-alfa 2a (PegIFNα-2a) and ribavirin therapy, on viral response and liver histology after liver transplantation (LT). METHODS: Hundred and one patients with recurrent HCV and a minimum of stage 1 fibrosis (METAVIR scoring), 1-5years after LT, were enrolled. PegIFNα-2a and...

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PMID: 22613001
DOI: 10.1016/j.jhep.2012.04.022

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