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SIRT1 gene polymorphisms and risk of lung cancer

1 Sept 2017

Abstract excerpt

Objective: Lung cancer, which is the leading cause of cancer death worldwide, is influenced by a wide variety of environmental and genetic risk factors. The silent information regulator 1 ( SIRT1 ) gene is located on the long arm of chromosome 10 (10q21.3) and has been shown to play crucial roles in lung cancer development in previous studies. In this study, we determined whether variation in the SIRT1 gene is...

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PMID: 28919817
DOI: 10.2147/cmar.s142677

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