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Article

Association of genetic polymorphisms in the paraoxonase 1 gene with the risk and prognosis of non-small cell lung cancer in Chinese Han population.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Mar 2012

Wang Hui, Li Lin, Ding Li, Zhang Zijin, Pu Chun

Abstract excerpt

OBJECTIVE: Oxidative stress and free radicals have been indicated to be associated with increased risk of various cancers. Paraoxonase 1 (PON1) gene, encoding PON1 protein, plays an important role as an endogenous free-radical scavenging molecule. The aim of the present study was to determine whether genetic polymorphisms of the PON1 gene are associated with the risk and prognosis of non-small cell lung cancer...

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Source

Identifiers

PMID: 22367101
DOI: 10.2310/JIM.0b013e318245d557

Genes

PON1

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