Article
A Combined Study of SLC6A15 Gene Polymorphism and the Resting-State Functional Magnetic Resonance Imaging in First-Episode Drug-Naive Major Depressive Disorder.
Genetic testing and molecular biomarkers - 1 Sept 2017
Wang Lijuan, Liu Zhifen, Cao Xiaohua, Li Jianying, Zhang Aixia, Sun Ning, Yang Chunxia, Zhang Kerang
Abstract excerpt
AIMS: The SLC6A15 gene has been identified as a novel candidate gene for major depressive disorder (MDD). However, the mechanism underlying the effects of how the SLC6A15 gene affects functional brain activity of patients with MDD remains unknown. METHODS: In the present study, we investigated the effect of the SLC6A15 gene polymorphism, rs1545843, on resting-state brain function in MDD with the imaging genomic...
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