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Article

Genotypic association of the DAOA gene with resting-state brain activity in major depression.

Molecular neurobiology - 1 Oct 2012

Chen Jun, Xu Yong, Zhang Juan, Liu Zhifen, Xu Cheng, Zhang Kerang, Shen Yan, Xu Qi

Abstract excerpt

Compelling evidence suggests that the glutamatergic system may contribute to the pathophysiology of major depression (MDD). While the D-amino acid oxidase activator (DAOA) gene can affect glutamatergic function, its genetic associations with MDD and abnormal resting-state brain activity have yet to be elucidated. A total of 488 patients with MDD and 480 controls were recruited to examine MDD association for the...

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Identifiers

PMID: 22851402
DOI: 10.1007/s12035-012-8294-5

Genes

DAOA

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