Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Precise insertion and guided editing of higher plant genomes using Cpf1 CRISPR nucleases.

Scientific reports - 14 Sept 2017

Begemann Matthew B, Gray Benjamin N, January Emma, Gordon Gina C, He Yonghua, Liu Haijun, Wu Xingrong, Brutnell Thomas P, Mockler Todd C, Oufattole Mohammed

Abstract excerpt

Precise genome editing of plants has the potential to reshape global agriculture through the targeted engineering of endogenous pathways or the introduction of new traits. To develop a CRISPR nuclease-based platform that would enable higher efficiencies of precise gene insertion or replacement, we screened the Cpf1 nucleases from Francisella novicida and Lachnospiraceae bacterium ND2006 for their capability to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR-Cas Systems
Share to Endonucleases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Editing

Share to Gene Targeting

Share to INDEL Mutation

Share to Mutagenesis, Insertional

Share to Plants

Share to Recombinational DNA Repair

Source

Open in PubMed Open full text

Identifiers

PMID: 28912524
DOI: 10.1038/s41598-017-11760-6
PMCID: PMC5599503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Precise insertion and guided editing of higher plant genomes using Cpf1 CRISPR nucleases.PMID 28912524Read ↗

Enhanced genome editing in rice using single transcript unit CRISPR ‐LbCpf1 systemsSemantic proximity Read ↗

Precision genetic modifications: a new era in molecular biology and crop improvement.Semantic proximity Read ↗

Targeted mutagenesis in rice using CRISPR-Cpf1 systemSemantic proximity Read ↗

Addition of the T5 exonuclease increases the prime editing efficiency in plants.Semantic proximity Read ↗

A large-scale whole-genome sequencing analysis reveals highly specific genome editing by both Cas9 and Cpf1 (Cas12a) nucleases in rice.Semantic proximity Read ↗

Cas9-PE: a robust multiplex gene editing tool for simultaneous precise editing and site-specific random mutation in rice.Semantic proximity Read ↗

The Cpf1 CRISPR-Cas protein expands genome-editing tools.Semantic proximity Read ↗

Generation of targeted mutant rice using a CRISPR-Cpf1 system.Semantic proximity Read ↗

Expanding base editing scope to near-PAMless with engineered CRISPR/Cas9 variants in plantsSemantic proximity Read ↗

Expanding the scope of plant genome engineering with Cas12a orthologs and highly multiplexable editing systems.Semantic proximity Read ↗

Efficient protein tagging and <i>cis</i> -regulatory element engineering via precise and directional oligonucleotide-based targeted insertion in plantsSemantic proximity Read ↗

The ScCas9++ variant expands the CRISPR toolbox for genome editing in plantsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.