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Article

Intratumor heterogeneity predicts metastasis of triple-negative breast cancer

28 Jun 2017

Abstract excerpt

Even with the identical clinicopathological features, the ability for metastasis is vastly different among triple-negative breast cancer (TNBC) patients. Intratumor heterogeneity (ITH), which is common in breast cancer, may be a key mechanism leading to the tumor progression. In this study, we studied whether a quantitative genetic definition of ITH can predict clinical outcomes in patients with TNBC. We...

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PMID: 28911002
DOI: 10.1093/carcin/bgx071

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